She died on the first approach of cold weather
Justine is orphaned pointedly about the same time (the previous November) that Victor Frankenstein gives life to his Creature, who is, like Justine, an unwanted dependant. Unlike every other character in the novel, however, the Creature is cut adrift from family protection not by death, but by a lack of human responsibility for his nurture. Born in abnormal circumstances, he is without family, wholly unaccommodated in an alien world. Where Alphonse Frankenstein virtually adopts Justine, his son rejects the Creature he has fashioned.