Writer. Born in Norwich, her father was the physician James Alderson (d. 1825). Brought up in progressive, Unitarian circles, she published poetry in the radical Norwich periodical, The Cabinet, in 1794. In 1798 she married the painter, John Opie (1761–1807; DNB) and moved to London, only returning to Norwich on his death in 1807. Opie contributed poems to Southey’s Annual Anthology (1799) and (1800) and became a prolific novelist after the success of Father and Daughter (1801). In 1825 she converted to Quakerism and devoted the rest of her life to charitable works.